Digestion : Early Diagnosis of Celiac Important

By a News Reporter-Staff News Editor at Gastroenterology Week -- Current study results on Gastroenterology have been published. According to news reporting originating in Seinajoki, Finland, by NewsRx journalists, research stated, "Evidence suggests that many coeliac disease patients suffer from persistent clinical symptoms and reduced health-related quality of life despite a strict gluten-free diet. We aimed to find predictors for these continuous health concerns in long-term treated adult coeliac patients."

The news reporters obtained a quote from the research from Central Hospital, "In a nationwide study, 596 patients filled validated Gastrointestinal Symptom Rating Scale and Psychological General Well-Being questionnaires and were interviewed regarding demographic data, clinical presentation and treatment of coeliac disease, time and place of diagnosis and presence of coeliac disease-associated or other co-morbidities.

Dietary adherence was assessed by a combination of self-reported adherence and serological tests. Odds ratios and 95% confidence intervals were calculated by binary logistic regression. Diagnosis at working age, long duration and severity of symptoms before diagnosis and presence of thyroidal disease, non-coeliac food intolerance or gastrointestinal co-morbidity increased the risk of persistent symptoms.

Patients with extraintestinal presentation at diagnosis had fewer current symptoms than subjects with gastrointestinal manifestations. Impaired quality of life was seen in patients with long duration of symptoms before diagnosis and in those with psychiatric, neurologic or gastrointestinal co-morbidities. Patients with persistent symptoms were more likely to have reduced quality of life. There were a variety of factors predisposing to increased symptoms and impaired quality of life in coeliac disease."

According to the news reporters, the research concluded: "Based on our results, early diagnosis of the condition and consideration of co-morbidities may help in resolving long-lasting health problems in coeliac disease."

For more information on this research see: Predictors of persistent symptoms and reduced quality of life in treated coeliac disease patients: a large cross-sectional study. BMC Gastroenterology, 2013;13():1-8. BMC Gastroenterology can be contacted at: Biomed Central Ltd, 236 Grays Inn Rd, Floor 6, London WC1X 8HL, England. (BioMed Central - www.biomedcentral.com/; BMC Gastroenterology - www.biomedcentral.com/bmcgastroenterol/)

Our news correspondents report that additional information may be obtained by contacting P. Paarlahti, Seinajoki Cent Hosp, Seinajoki, Finland (see also Gastroenterology).

Keywords for this news article include: Europe, Finland, Seinajoki, Quality of Life, Gastroenterology

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