1825
Table of Contents > Health Dictionary > Leukoencephalopathy with vanishing white matter

Leukoencephalopathy with vanishing white matter

Rare autosomal recessive disorder marked by extensive cystic degeneration of white matter, due to mutations in the genes for the subunits of eukaryotic initiation factor 2B, a heteropentameric guanine nucleotide exchange factor that regulates cell translation.
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