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Table of Contents > Health Dictionary > Lesch-Nyhan syndrome

Lesch-Nyhan syndrome

A rare and usually fatal genetic disorder of male children that is inherited as an X-linked recessive trait and is characterized by hyperuricemia, mental retardation, spasticity, compulsive biting of the lips and fingers, and a deficiency of hypoxanthine-guanine phosphoribosyltransferase. Also referred to as Lesch-Nyhan disease.
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